Influence of process temperature and residence time on the manufacturing of amorphous solid dispersions in hot melt extrusion
Author:
Affiliation:
1. Laboratory of Solids Process Engineering, TU Dortmund University, Dortmund, Germany
2. INVITE GmbH, Drug Delivery Innovation Center, Leverkusen, Germany
3. Laboratory of Thermodynamics, TU Dortmund University, Dortmund, Germany
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/10837450.2022.2051549
Reference34 articles.
1. Stability-enhanced Hot-melt Extruded Amorphous Solid Dispersions via Combinations of Soluplus® and HPMCAS-HF
2. How changes in molecular weight and PDI of a polymer in amorphous solid dispersions impact dissolution performance
3. Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs
4. Physikalische Werkstoffdiagnostik
5. Surface area normalized dissolution to study differences in itraconazole-copovidone solid dispersions prepared by spray-drying and hot melt extrusion
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