1. Department of Biology and Environment, University of Trás-os Montes e Alto Douro (UTAD), Vila Real, Portugal;
2. Centre for Research and Technology of Agro-Environmental and Biological Sciences (CITAB-UTAD), Vila Real, Portugal;
3. Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra (FFUC), Coimbra, Portugal;
4. Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto (FCUP), Porto, Portugal;
5. CEB - Centre of Biological Engineering, University of Minho, Braga, Portugal