Manipulation of Radiobiological Hypoxia in a Human Melanoma Xenograft to Exploit the Bioreductive Cytotoxicity of RSU-1069
Author:
Publisher
Informa UK Limited
Subject
Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology
Link
http://www.tandfonline.com/doi/pdf/10.1080/09553008914551781
Reference12 articles.
1. Radiation sensitization and chemopotentiation: Rsu 1069, a compound more efficient than misonidazole in vitro and in vivo
2. The effect of hydralazine on the tumor cytotoxicity of the hypoxic cell cytotoxin RSU-1069: Evidence for therapeutic gain
3. The radiosensitizing and toxic effects of RSU-1069 on hypoxic cells in a murine tumor
4. Experimental pharmacokinetics of rsu-1069 and its analogues: High tumor/plasma ratios
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1. Bioreductive drugs for cancer therapy: The search for tumor specificity;International Journal of Radiation Oncology*Biology*Physics;1994-05
2. Assessing the bioreductive effectiveness of the nitroimidazole RSU1069 and its prodrug RB6145: with particular reference toin vivo methods of evaluation;Cancer and Metastasis Reviews;1993-06
3. Bioreducible mustards: a paradigm for hypoxia-selective prodrugs of diffusible cytotoxins (HPDCs);Cancer and Metastasis Reviews;1993-06
4. Use of Fluorine-19 Nuclear Magnetic Resonance Spectroscopy and Hydralazine for Measuring Dynamic Changes in Blood Perfusion Volume in Tumors in Mice;JNCI Journal of the National Cancer Institute;1992-02-05
5. Magnetic resonance spectroscopy studies on experimental murine and human tumors: Comparison of changes in phosphorus metabolism with induced changes in vascular volume;International Journal of Radiation Oncology*Biology*Physics;1992-01
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