Lipase-catalyzed domino Michael–aldol reaction of 2-methyl-1,3-cycloalkanedione and methyl vinyl ketone for the synthesis of bicyclic compounds
Author:
Affiliation:
1. Division of Applied Sciences, Muroran Institute of Technology, Muroran, Japan
2. Tokiwakai Group, Fukushima, Japan
3. Amano Enzyme Inc., Gifu Research and Development Center, Gifu, Japan
Funder
Financial support from an MuIT Grant for Selected Research is gratefully acknowledged.
Publisher
Informa UK Limited
Subject
Organic Chemistry
Link
https://www.tandfonline.com/doi/pdf/10.1080/00397911.2015.1116584
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1. Highly enantioselective synthesis of warfarin and its analogs by means of cooperative LiClO4/DPEN-catalyzed Michael reaction: enantioselectivity enhancement and mechanism
2. Rhodium-Catalyzed Enantioselective Reductive Aldol Reaction
3. Lipase catalysed Michael addition of secondary amines to acrylonitrile
4. Amino Acid Catalyzed Direct Asymmetric Aldol Reactions: A Bioorganic Approach to Catalytic Asymmetric Carbon−Carbon Bond-Forming Reactions
5. High-Yielding Synthesis of the Anti-Influenza Neuramidase Inhibitor (−)-Oseltamivir by Three “One-Pot” Operations
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