Efficient Synthesis of Substances Related to Cinacalcet Hydrochloride via Heck Coupling

Author:

Lei Fan1,Qu Boyi1,Li Xiaolong1,Guo Li1,Guan Mei2,Hai Li1,Jin Hui1,Wu Yong1

Affiliation:

1. a Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy , Sichuan University , Chengdu , China

2. b West China Hospital , Sichuan University , Chengdu , Sichuan , China

Funder

We sincerely thank the Sichuan Provincial Science and Technology Support Program (Grant No. 2011SZ0014). Also, we express our gratitude for the support from Sichuan Bali Pharmaceutical Co., Ltd.

Publisher

Informa UK Limited

Subject

Organic Chemistry

Reference9 articles.

1. Therapeutic Use of Calcimimetics

2. Nemeth , E. F. Van , W. B. C. Balandrin , M. F. Del Mar , E. G. Moe , S. T. U. S. Patent 6011068, January 4, 2000 .

3. Practical synthesis of the calcimimetic agent, cinacalcet

4. Efficient Synthesis of Cinacalcet Hydrochloride

5. (a) ICH Guidelines, Q3A (R): Impurities in New Drug Substances. International Conference of Harmonisation, Geneva, Switzerland, February 2002; (b) ICH Guidelines, Q3B (R): Impurities in New Drug Products. International Conference of Harmonisation, Geneva, Switzerland, February 2002; (c) Impurities Guidelines for Residual Solvents, Q3(c). International Conference on Harmonisation, Geneva, Switzerland, 1997 .

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