Cu(OTf)2-catalyzed synthesis of highly substituted 1-methoxy imidazoles via (3 + 2) cycloaddition between imino carbenoids and nitriles

Author:

Kuruba Bharath Kumar1,Vasanthkumar Samuel1,Emmanuvel Lourdusamy1

Affiliation:

1. School of Science and Humanities, Department of Chemistry, Karunya University, Karunya Nagar, Coimbatore, Tamil Nadu, India

Funder

The authors thank the Department of Science and Technology, SERB, New Delhi, for funding to carry out this research work.

Publisher

Informa UK Limited

Subject

Organic Chemistry

Reference10 articles.

1. (a) Katrizky, A. R.; Ramsden, C. A.; Scriven, E. F. V.; Taylor, R. J. K. In Comprehensive Heterocyclic Chemistry III; Joule, J. (Ed.); Elsevier: Oxford, 2008; p. 4; (b) Joule, J.; Mills, K. Heterocyclic Chemistry, 5th ed.; John Wiley & Sons: Chichester, UK, 2010; (c) Bhatnagar, A.; Sharma, P. K.; Kumar, N. Int. J. Pharm. Tech. Res. 2011, 3, 268; (d) Babizhayev, M. A. Life Sci. 2006, 78, 2343; (e) Narasimhan, B.; Dharma, D.; Kumar, P. Med. Chem. Res. 2011, 20, 1119; (f) Williams, D. A.; Lemke, T. L.; Foye, W. O. Foye’s Principles of Medicinal Chemistry, 5th ed. Lippincott Williams & Wilkins: New York, 2002; p. 36. (g) Pandeya Nath, S. N. A Text Book of Medicinal Chemistry; SG publisher, 2004, vol. 1, no. 3, pp. 2–3.

2. A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

3. Imidazol- und Benzimidazol-N-oxide

4. Synthesis of 2-Substituted 1-Hydroxyimidazoles through Directed Lithiation

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