Facile synthesis of cyclopentapeptide, cyclo[Arg(NO2)-Gly-Asp(OBn)-D-Phe-Lys(Fmoc)], and its application in synthesis of integrin-targeting anticancer conjugate-Reference-Cited by-同舟云学术

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Facile synthesis of cyclopentapeptide, cyclo[Arg(NO2)-Gly-Asp(OBn)-D-Phe-Lys(Fmoc)], and its application in synthesis of integrin-targeting anticancer conjugate

Published:2017-10-05 Issue:21 Volume:47 Page:1985-1989
ISSN:0039-7911
Container-title:Synthetic Communications
language:en
Short-container-title:Synthetic Communications

Author:

Ma Da-You¹,Zhong Tao¹,Wang Long-Long¹,Liu Li-Jun²,Wang Ying-Xiong³,Liu Su-You¹

Affiliation:

1. School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, China

2. School of Life Sciences, Central South University, Changsha, Hunan, China

3. Shanxi Engineering Research Center of Biorefinery, Chinese Academy of Sciences, Institute of Coal Chemistry, Taiyuan, Shanxi, China

Funder

National Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

Organic Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/00397911.2017.1359626

Reference10 articles.

1. Integrin-epigenetics: a system with imperative impact on cancer

2. Conformation/activity studies of rationally designed potent anti-adhesive RGD peptides

3. Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation

4. Evaluation of two novel 64Cu-labeled RGD peptide radiotracers for enhanced PET imaging of tumor integrin αvβ3

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