Identification, synthesis and strategy for minimization of potential impurities in the synthesis of suvorexant-Reference-Cited by-同舟云学术

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Identification, synthesis and strategy for minimization of potential impurities in the synthesis of suvorexant

Published:2021-05-24 Issue:14 Volume:51 Page:2225-2236
ISSN:0039-7911
Container-title:Synthetic Communications
language:en
Short-container-title:Synthetic Communications

Author:

Lv Xunlei¹²,Pan Jing¹²,Liu Weiyuan²,Meng Xue²,Chen Liang²,Zhou Ting²,Lin Kuaile²,Ye Deyong¹,Zhou Weicheng²

Affiliation:

1. School of Pharmacy, Fudan University, Shanghai, China

2. State Key Laboratory of New Drug and Pharmaceutical Process, Shanghai Key Laboratory of Anti-infectives, State Institute of Pharmaceutical Industry, Shanghai, China

Publisher

Informa UK Limited

Subject

Organic Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/00397911.2021.1930055

Reference11 articles.

1. Profile of suvorexant in the management of insomnia

2. Laboratory and practical synthesis of Suvorexant, a selective dual orexin receptor antagonist

3. Facile synthesis of suvorexant, an orexin receptor antagonist, via a chiral diazepane intermediate

4. Reaction Development and Mechanistic Study of a Ruthenium Catalyzed Intramolecular Asymmetric Reductive Amination en Route to the Dual Orexin Inhibitor Suvorexant (MK-4305)

5. Enantioselective Synthesis of a Dual Orexin Receptor Antagonist

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1. Synthesis, structural characterization of optical isomers and potential impurities in Alalevonadifloxacin mesylate;Synthetic Communications;2023-01-03

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