Acylimidazolides as Versatile Synthetic Intermediates for the Preparation of Sterically Congested Amides and Ketones: A Practical Synthesis of Proscar®

Author:

Bhattacharya A.,Williams J. M.,Amato J. S.,Dolling U.-H.,Grabowski E. J. J.

Publisher

Informa UK Limited

Subject

Organic Chemistry

Reference25 articles.

1. Azasteroids as inhibitors of rat prostatic 5.alpha.-reductase

2. Azasteroids: structure-activity relationships for inhibition of 5.alpha.-reductase and of androgen receptor binding

3. The first commercially important product to arise from the family of 5α-reductase inhibitors will be marketed as Proscar® by Merck and Co

4. Silylation-mediated oxidation of 4-aza-3-ketosteroids with DDQ proceeds via DDQ-substrate adducts

5. Ogliaruso, M. A. and Wolfe, J. F. 1979.The Chemistry of Acid Derivatives, Edited by: Patai, S. 474New York: John Wiley & Sons. Part 1

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