Hydration of drug molecules: cavityinclusion of water in crystals of loperamide hydrochloride tetrahydrate

Author:

Caira Mino R.1,Gerber Jan J.2,Lötter Antonie P.2

Affiliation:

1. a Department of Chemistry , University of Cape Town , Rondebosch , 7700 , South Africa

2. b Research Institute for Industrial Pharmacy, Potchefstroom University for Christian Higher Education , Potchefstroom , 2520 , South Africa

Publisher

Informa UK Limited

Subject

General Chemistry

Reference17 articles.

1. Van Rompay , J. and Carter , J. E. 1990.Analytical Profiles of Drug Substances, Edited by: Florey , K. Vol. 19, 341–365. San Diego, California: Academic Press.

2. 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenylpiperidine-1-butyramide (loperamide) hydrate

3. Byrn , S. R. 1982.Solid-State Chemistry of Drugs, 151–155. Academic Press.

4. Dean , P. M. 1987.Molecular Foundations of Drug-Receptor Interaction, 188–235. Cambridge, England: Cambridge University Press.

5. Physical Characterization of the Hydrates of Urapidil

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