Establishing short-term occupational exposure limits (STELs) for sensory irritants using predictive and <i>in silico</i> respiratory rate depression (RD <sub>50</sub> ) models-Reference-Cited by-同舟云学术

Establishing short-term occupational exposure limits (STELs) for sensory irritants using predictive and in silico respiratory rate depression (RD ₅₀ ) models

Published:2024-01-02 Issue:1 Volume:36 Page:13-25
ISSN:0895-8378
Container-title:Inhalation Toxicology
language:en
Short-container-title:Inhalation Toxicology

Author:

Russell Anthony J.¹,Vincent Melissa¹²,Buerger Amanda N.¹²,Dotson Scott¹³,Lotter Jason³⁴,Maier Andrew¹⁵

Affiliation:

1. Stantec (ChemRisk), Cincinnati, OH, USA;

2. Tox Strategies, Ashville, NC, USA

3. Insight Exposure and Risk Sciences Group, Cincinnati, OH, USA

4. Stantec (ChemRisk), Chicago, IL, USA

5. Occupational Alliance for Risk Science, Cincinnati, OH, USA

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/08958378.2023.2299867

Reference58 articles.

1. Reliable prediction of sensory irritation threshold values of organic compounds using new models based on linear free energy relationships and GC×GC retention parameters

2. Abraham M, Sánchez-Moreno R, Gil-Lostes J, Cometto m J, Cain W. 2010. Chapter 25, Physicochemical modeling of sensory irritation in humans and experimental animals. In: Toxicology of the nose and upper airways. San Diego (CA): UC San Diego; p. 376–389.

3. [ACGIH] American Conference of Governmental Industrial Hygenists. 2020. Operations manual threshold limit (TLV) for chemical substances committee. Last Revised: 2020 Nov 7. Cincinnati (OH): American Conference of Governmental Industrial Hygenists. [accessed 2023 Apr 17]. https://www.acgih.org/wp-content/uploads/2021/02/Operations-Manual-TLV-CS_11-7-2020.pdf.

4. Physicochemical Properties of Nonreactive Volatile Organic Chemicals to Estimate RD50: Alternatives to Animal Studies

5. Estimating the Sensory Irritating Potency of Airborne Nonreactive Volatile Organic Chemicals and Their Mixtures