Covariance and variance evaluations of two estimators for drug–placebo difference in a trial with sequential parallel design
Author:
Affiliation:
1. Janssen China, Xinmei Union Square, Shanghai, China
2. Jassen Pharmaceutical L.L.C., Titusville, USA
Publisher
Informa UK Limited
Subject
Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/03610926.2016.1205613
Reference6 articles.
1. Evaluation of performance of some enrichment designs dealing with high placebo response in psychiatric clinical trials
2. The Problem of the Placebo Response in Clinical Trials for Psychiatric Disorders: Culprits, Possible Remedies, and a Novel Study Design Approach
3. Erratum
4. Doubly Randomized Delayed-Start Design for Enrichment Studies with Responders or Nonresponders
5. An examination of the efficiency of the sequential parallel design in psychiatric clinical trials
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2. Sequential parallel comparison design for “gold standard” noninferiority trials with a prespecified margin;Biometrical Journal;2019-08-28
3. Statistical inference problems in sequential parallel comparison design;Journal of Biopharmaceutical Statistics;2019-04-29
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