Overdose intake of Neu5Gc triggers colorectal inflammation and alters liver metabolism

Author:

Yuan Teng1,Yang Peidong1,Zhang Anjing1,Li Jing1,Han Ziyin1,Yang Shuqi1,Jimu Yihamu1,Kong Fanli2,Pan Dengke34,Long Keren1,Li Mingzhou1,Lu Lu1

Affiliation:

1. State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, People’s Republic of China

2. College of Life Science, Sichuan Agricultural University, Ya'an, People’s Republic of China

3. Clinical Immunology Translational Medicine Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, People’s Republic of China

4. Chengdu Sino-Clone Organ Biotechnology, Co., Ltd, Chengdu, People’s Republic of China

Funder

National Key R & D Program of China

the National Natural Science Foundation of China

the Science Foundation of the Sichuan Province

the China Postdoctoral Science Foundation

the Major Science and Technology Projects of Tibet Autonomous Region

the A'Ba Science and Technology Program

Publisher

Informa UK Limited

Subject

Agronomy and Crop Science,Immunology,Food Science

Reference56 articles.

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2. Mechanism of Uptake and Incorporation of the Non-human Sialic Acid N-Glycolylneuraminic Acid into Human Cells*

3. Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer: French NutriNet-Santé study

4. Bedi A. Pasricha P. J. Akhtar A. J. Barber J. P. Bedi G. C. Giardiello F. M. Zehnbauer B. A. Hamilton S. R. & Jones R. J. (1995). Inhibition of apoptosis during development of colorectalcancer. Cancer Research 55 (9) 1811–1816.

5. Profiling anti-Neu5Gc IgG in human sera with a sialoglycan microarray assay;Ben-Arye S L.;Journal of Visualized Experiments,2017

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