Deciphering the structural and functional impact of Q657L mutation in <i>NLRC4</i> using computational methods-Reference-Cited by-同舟云学术

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Deciphering the structural and functional impact of Q657L mutation in NLRC4 using computational methods

Published:2022-05-30 Issue:14 Volume:48 Page:1240-1255
ISSN:0892-7022
Container-title:Molecular Simulation
language:en
Short-container-title:Molecular Simulation

Author:

Chear Chai Teng¹²^ORCID,Mat Ripen Adiratna¹^ORCID,Mohamad Saharuddin Bin²³^ORCID

Affiliation:

1. Primary Immunodeficiency Unit, Allergy and Immunology Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Selangor, Malaysia

2. Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia

3. Centre of Research in Systems Biology, Structural Bioinformatics and Human Digital Imaging (CRYSTAL), Universiti Malaya, Kuala Lumpur, Malaysia

Funder

Ministry of Health, Malaysia

Publisher

Informa UK Limited

Subject

Condensed Matter Physics,General Materials Science,General Chemical Engineering,Modeling and Simulation,Information Systems,General Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/08927022.2022.2080822

Reference68 articles.

1. Systemic autoinflammatory diseases

2. Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee

3. The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammation

4. Novel aspects of the assembly and activation of inflammasomes with focus on the NLRC4 inflammasome

5. Crystal Structure of NLRC4 Reveals Its Autoinhibition Mechanism

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