Kv1.3 inhibition attenuates neuroinflammation through disruption of microglial calcium signaling
Author:
Affiliation:
1. Department of Physiology and Membrane Biology, University of California, Davis, CA, USA
2. Department of Pharmacology, University of California, Davis, CA, USA
Funder
National Institute of Neurological Disease
UC Davis School of Medicine Research Partnership
Publisher
Informa UK Limited
Subject
Biochemistry,Biophysics
Link
https://www.tandfonline.com/doi/pdf/10.1080/19336950.2020.1853943
Reference61 articles.
1. Voltage-gated K+ channels in human T lymphocytes: a role in mitogenesis?
2. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases
3. Durable Pharmacological Responses from the Peptide ShK-186, a Specific Kv1.3 Channel Inhibitor That Suppresses T Cell Mediators of Autoimmune Disease
4. Peptide blockers of K v 1.3 channels in T cells as therapeutics for autoimmune disease
5. Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke
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