CD4+ memory T cells infected with latent HIV-1 are susceptible to drugs targeting telomeres
Author:
Affiliation:
1. Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA
Funder
National Institute of Allergy and Infectious Diseases
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Publisher
Informa UK Limited
Subject
Cell Biology,Developmental Biology,Molecular Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15384101.2018.1520568
Reference76 articles.
1. Reservoirs for HIV-1: Mechanisms for Viral Persistence in the Presence of Antiviral Immune Responses and Antiretroviral Therapy
2. Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane
3. Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo
4. Paired quantitative and qualitative assessment of the replication-competent HIV-1 reservoir and comparison with integrated proviral DNA
5. Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics
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