Mathematical model identifies effective P53 accumulation with target gene binding affinity in DNA damage response for cell fate decision
Author:
Affiliation:
1. School of Life Sciences, Anqing Normal University, Anqing, Anhui, China
2. MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, China
Funder
Key Project ofNatural Science Foundation of Anhui Provincial EducationDepartment
Publisher
Informa UK Limited
Subject
Cell Biology,Developmental Biology,Molecular Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15384101.2018.1553342
Reference48 articles.
1. Encoding and Decoding Cellular Information through Signaling Dynamics
2. Is there a code embedded in proteins that is based on post-translational modifications?
3. Specificity and stability of transient protein–protein interactions
4. p53 Dynamics Control Cell Fate
5. Recurrent design patterns in the feedback regulation of the mammalian signalling network
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