p27 inhibits CDK6/CCND1 complex formation resulting in cell cycle arrest and inhibition of cell proliferation
Author:
Affiliation:
1. State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University, Chongqing, China
Funder
National Natural Science Foundation of China
Hi-Tech Research and Development 863 Program of China
China Agriculture Research System
Publisher
Informa UK Limited
Subject
Cell Biology,Developmental Biology,Molecular Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15384101.2018.1526598
Reference22 articles.
1. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
2. Genetic characterization of p27kip1and stathmin in controlling cell proliferation in vivo
3. Temporal Distribution of CDK4, CDK6, D-Type Cyclins, and p27 in Developing Mouse Oocytes1
4. Molecular mechanisms underlying interferon-α-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins
5. Steroid- and retinoid-mediated growth arrest and apoptosis in WEHI-231 cells: role of NF-κB, c-Myc and CKI p27Kip1
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