Elevated intracellular pH appears in aged oocytes and causes oocyte aneuploidy associated with the loss of cohesion in mice
Author:
Affiliation:
1. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
2. University of Chinese Academy of Sciences, Beijing, China
Publisher
Informa UK Limited
Subject
Cell Biology,Developmental Biology,Molecular Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15384101.2016.1201255
Reference50 articles.
1. Age-associated increase in aneuploidy and changes in gene expression in mouse eggs
2. Human aneuploidy: mechanisms and new insights into an age-old problem
3. Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes
4. Meiotic Origins of Maternal Age-Related Aneuploidy1
5. Age‐related aneuploidy through cohesion exhaustion
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