Clinical stage molecule PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.-Reference-Cited by-同舟云学术

Clinical stage molecule PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.

Published:2020-12-11 Issue:24 Volume:19 Page:3632-3638
ISSN:1538-4101
Container-title:Cell Cycle
language:en
Short-container-title:Cell Cycle

Author:

Theise Neil D.¹²^ORCID,Arment Anthony R.³,Chakravarty Dimple⁴,Gregg John M. H.²,Jacobson Ira M.⁵,Jung Kie Hoon⁶,Nair Sujit S.⁴,Tewari Ashutosh K.⁴,Thurston Archie W.⁷,Van Drie John⁸,Westover Jonna B.⁶

Affiliation:

1. Department of Pathology, New York University-Grossman School of Medicine, New York, NY, USA

2. Palisades Therapeutics/Pop Test Oncology LLC, Cliffside Park, NJ, USA

3. Department of Biology, Central State University, Wilberforce, OH, USA

4. Department of Urology and the Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

5. Department of Medicine, New York University-Grossman School of Medicine, New York, NY, USA

6. Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT, USA

7. ADME Solutions, Inc, San Diego, CA, USA

8. Van Drie Research, North Andover, MA, USA

Funder

NIH

NIAID

Palisades Therapeutics/Pop Test Oncology LLC

Publisher

Informa UK Limited

Subject

Cell Biology,Developmental Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15384101.2020.1859752

Reference36 articles.

1. Pan-cancer analysis to identify a novel class of glucocorticoid and androgen receptor antagonists with potent anti-tumor activity.

2. Short ReviewGlucocorticoid Receptor Antagonists: New Tools to Investigate Disorders Characterized by Cortisol Hypersecretion

3. The long-acting β2-adrenoceptor agonist, indacaterol, enhances glucocorticoid receptor-mediated transcription in human airway epithelial cells in a gene- and agonist-dependent manner

4. Retinazone Inhibits Certain Blood-Borne Human Viruses Including Ebola Virus Zaire

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