DFNA5 inhibits colorectal cancer proliferation by suppressing the mTORC1/2 signaling pathways via upregulation of DEPTOR
Author:
Affiliation:
1. Department of General Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China
2. Department of Emergency, Ankang People’s Hospital, Ankang, Shaanxi, China
Funder
National Natural Science Foundation of China
The Coordinative and Innovative Plan Projects of the Science and Technology Program in Shaanxi Province
Fundamental Research Funds for the Central Universities
The institutional foundation of the first affiliated hospital of Xi’an Jiaotong University
Publisher
Informa UK Limited
Subject
Cell Biology,Developmental Biology,Molecular Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15384101.2022.2088570
Reference47 articles.
1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2. Oxaliplatin, Fluorouracil, and Leucovorin as Adjuvant Treatment for Colon Cancer
3. The Molecular Pathogenesis of Colorectal Cancer and Its Potential Application to Colorectal Cancer Screening
4. Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
5. Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma
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