Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication-Reference-Cited by-同舟云学术

Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication

Published:2016-01-17 Issue:2 Volume:15 Page:274-282
ISSN:1538-4101
Container-title:Cell Cycle
language:en
Short-container-title:Cell Cycle

Author:

De Santis Puzzonia Marco¹²,Gonzalez Laetitia³,Ascenzi Sonia¹,Cundari Enrico¹,Degrassi Francesca¹

Affiliation:

1. Institute of Molecular Biology and Pathology, CNR National Research Council, Rome, Italy

2. Sapienza University, Department of Cellular Biotechnology and Hematology, Rome, Italy

3. Vrije Universiteit Brussel, Laboratory of Cell Genetics, Brussels, Belgium

Publisher

Informa UK Limited

Subject

Cell Biology,Developmental Biology,Molecular Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15384101.2015.1127469

Reference40 articles.

1. The Causes and Consequences of Polyploidy in Normal Development and Cancer

2. The consequences of tetraploidy and aneuploidy

3. 2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells

4. Limiting the Proliferation of Polyploid Cells

5. Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution

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