An Alternative Synthesis of 2-Chloro-5-Hydroxypyridine: A Key Component of the Non-Opioid Analgesic Agent ABT-594
Author:
Publisher
Informa UK Limited
Subject
Organic Chemistry
Link
http://www.tandfonline.com/doi/pdf/10.1080/00397910008087025
Reference9 articles.
1. Broad-Spectrum, Non-Opioid Analgesic Activity by Selective Modulation of Neuronal Nicotinic Acetylcholine Receptors
2. Identification and Initial Structure−Activity Relationships of (R)-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors
3. Efficient asymmetric synthesis of ABT-594; a potent, orally effective analgesic
4. Preparation and Properties of Pyridine-Analogue of TCNQ Dianion Salt
5. A total synthesis of (±)-epibatidine
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3. Efficient synthesis of halohydroxypyridines by hydroxydeboronation;Tetrahedron;2005-02
4. Ring nitrogen-substituted non-steroidal estrogens: pyridine and pyrimidine analogs of the phenol in deoxyhexestrol experience resonance constraints on preferred ligand conformation;Bioorganic & Medicinal Chemistry Letters;2004-12
5. Synthesis of novel halopyridinylboronic acids and esters. Part 3: 2, or 3-Halopyridin-4-yl-boronic acids and esters;Tetrahedron;2002-05
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