Isotope Effects during Metabolism of (+)- and (−)- Trans Tramadol Isotopomers by Human Liver Microsomes
Author:
Publisher
Informa UK Limited
Subject
Inorganic Chemistry,General Environmental Science,Environmental Chemistry
Link
http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883
Reference6 articles.
1. Isotope Effects During Metabolism of (±)-Tramadol Isotopomers by Human Liver Microsomes
2. The metabolism of tramadol by human liver microsomes
3. Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism) — Increased michaelis constant (km) and loss of stereoselectivity of bufuralol 1′-hydroxylation in poor metabolizers
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1. Comparative metabolism of tramadol and tapentadol: a toxicological perspective;Drug Metabolism Reviews;2016-09-15
2. Stereoselective pharmacokinetic analysis of tramadol and its main phase I metabolites in healthy subjects after intravenous and oral administration of racemic tramadol;Biopharmaceutics & Drug Disposition;2006
3. Simultaneous stereoselective analysis of tramadol and its primary phase I metabolites in plasma by liquid chromatography;Journal of Chromatography A;2004-03
4. Labelling Studies for Structure Elucidation of a New Hydroxymetabolite of Tramadol;Isotopes in Environmental and Health Studies;1998-09
5. High-Performance liquid chromatographic assay for the simultaneous determination of tramadol and its metabolites in microsomal fractions of human liver;Journal of Chromatography B: Biomedical Sciences and Applications;1996-11
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