1. Amgen Research, Thousand Oaks, CA, USA;
2. Genentech Inc., South San Francisco, CA, USA
3. Division of Medicinal Safety Science, National Institute of Health Sciences, Tokyo, Japan;
4. Department and Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan;
5. University of Liverpool, Liverpool, UK;
6. Faculty of Pharmacy and Medicine, University of Toronto, Toronto, Canada;