Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer
Author:
Affiliation:
1. Integrative Oncology, BC Cancer, Vancouver, Canada
2. Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
3. Interdisciplinary Oncology, University of British Columbia, Vancouver, Canada
Funder
CIHR
Strategic Training in Transdisciplinary Radiation Science for the 21st Century
Cordula and Gunter Paetzold Fellowship
Publisher
Informa UK Limited
Subject
Oncology,Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1959978
Reference29 articles.
1. B cells, plasma cells and antibody repertoires in the tumour microenvironment
2. Tertiary lymphoid structures improve immunotherapy and survival in melanoma
3. B cells are associated with survival and immunotherapy response in sarcoma
4. B cells and tertiary lymphoid structures promote immunotherapy response
5. Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
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1. Oxygen level is a critical regulator of human B cell differentiation and IgG class switch recombination;Frontiers in Immunology;2022-12-14
2. Hypoxia orchestrates the lymphovascular–immune ensemble in cancer;Trends in Cancer;2022-09
3. Promise of hypoxia-targeted tracers in metastatic lymph node imaging;European Journal of Nuclear Medicine and Molecular Imaging;2022-08-22
4. Effect of lncRNA00511 on Non-Small Cell Lung Cancer by Regulating miR-29b-3p;Journal of Biomaterials and Tissue Engineering;2022-08-01
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