Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma

Author:

Bordry Natacha12ORCID,Broggi Maria A. S.23ORCID,de Jonge Kaat1ORCID,Schaeuble Karin1,Gannon Philippe O.4,Foukas Periklis G.45,Danenberg Esther4,Romano Emanuela46,Baumgaertner Petra14,Fankhauser Manuel2ORCID,Wald Noémie1,Cagnon Laurène4,Abed-Maillard Samia4ORCID,Hajjami Hélène Maby-El1ORCID,Murray Timothy1,Ioannidou Kalliopi1ORCID,Letovanec Igor7ORCID,Yan Pu7,Michielin Olivier4,Matter Maurice45ORCID,Swartz Melody A.28,Speiser Daniel E.14ORCID

Affiliation:

1. Clinical Tumor Biology and Immunotherapy Group, Department of Oncology and Ludwig Cancer Research, University of Lausanne (UNIL), Lausanne, Switzerland

2. Institute of Bioengineering and Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

3. Institute for Molecular Engineering, University of Chicago, Chicago, IL, USA

4. Department of Oncology, Lausanne University Hospital Center (CHUV) and University of Lausanne, Lausanne, Switzerland

5. Department of Surgery, CHUV, Lausanne, Switzerland

6. Department of Oncology, INSERM U932, Institut Curie, Paris, FRANCE

7. Department of Pathology, CHUV, Lausanne, Switzerland

8. 2nd Department of Pathology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece

Funder

Swiss cancer league

Swiss National Science Foundation (SNSF)

Swiss transmed

EC | European Research Council (ERC)

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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