A loss-of-function polymorphism in ATG16L1 compromises therapeutic outcome in head and neck carcinoma patients

Author:

Le Naour Julie123ORCID,Sztupinszki Zsofia456ORCID,Carbonnier Vincent123,Casiraghi Odile7,Marty Virginie8,Galluzzi Lorenzo91011,Szallasi Zoltan456,Kroemer Guido121213ORCID,Vacchelli Erika12ORCID

Affiliation:

1. Equipe labellisée par la Ligue contre le cancer, Université de Paris, Sorbonne Université, INSERM U1138, Centre de Recherche des Cordeliers, Institut Universitaire de France, Paris, France

2. Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France

3. Université Paris Sud, Paris Saclay, Faculty of Medicine Kremlin Bicêtre, France

4. Computational Health Informatics Program (CHIP), Boston Children’s Hospital, Boston, MA, USA

5. Harvard Medical School, Boston, MA, USA

6. Danish Cancer Society Research Center, Copenhagen, Denmark

7. Department of Head and Neck Surgical and Medical Oncology, Gustave Roussy Cancer Campus, Paris-Saclay University, Villejuif, France

8. Experimental and Translational Pathology Platform (PETRA), AMMICa Inserm US23/UMS CNRS3655, Gustave Roussy Cancer Campus, Villejuif, France

9. Department of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA

10. Sandra and Edward Meyer Cancer Center, New York, NY, USA

11. Caryl and Israel Englander Institute for Precision Medicine, New York, NY, USA

12. Institut du Cancer Paris CARPEMAP-HP, Hôpital Européen Georges Pompidou, Pôle de Biologie, Paris, France

13. Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France

Funder

The author(s) reported there is no funding associated with the work featured in this article

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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