An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial-Reference-Cited by-同舟云学术

An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial

Published:2020-01-01 Issue:1 Volume:9 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Charles Julie¹²,Chaperot Laurence¹³,Hannani Dalil⁴,Bruder Costa Juliana¹²³,Templier Isabelle²,Trabelsi Sabiha²,Gil Hugo⁵,Moisan Anaick¹⁶,Persoons Virginie⁶,Hegelhofer Harald⁶,Schir Edith⁷,Quesada Jean-Louis⁸,Mendoza Christophe⁸,Aspord Caroline¹³,Manches Olivier¹³,Coulie Pierre G.⁹,Khammari Amir¹⁰,Dreno Brigitte¹⁰,Leccia Marie-Thérèse¹²,Plumas Joel¹³⁴

Affiliation:

1. Immunobiology and Immunotherapy of Chronic Diseases, Institute for Advanced Biosciences, Inserm U 1209, CNRS UMR 5309, Université Grenoble Alpes, Grenoble, France

2. Dermatology Department, Pôle Pluridisciplinaire de Médecine, CHU Grenoble Alpes, Grenoble, France

3. R&D Laboratory, Etablissement Français du Sang Auvergne-Rhône-Alpes, Grenoble, France

4. Immune checkpoint inhibitors, PDC*line Pharma, Grenoble

5. Pathology Department, Institut de Biologie et Pathologie, CHU Grenoble Alpes, Grenoble, France

6. Cell Therapy and Engineering Unit, Etablissement Français du Sang Auvergne-Rhône-Alpes, Saint Ismier, France

7. Délégation à la Recherche Clinique et à l’Innovation, CHU Grenoble Alpes, Grenoble, France

8. Centre d’investigation Clinique, CHU Grenoble Alpes, Grenoble, France

9. de Duve Institute, Université Catholique de Louvain, Brussels, Belgium

10. Onco-dermatology Department, CHU Nantes, CIC 1413, CRCINA, Nantes University, Nantes, France

Funder

Etablissement Français du Sang

Ligue Contre le Cancer

Proof-of-concept CLARA

Fondation SILAB

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2020.1738812

Reference40 articles.

1. An immune-active tumor microenvironment favors clinical response to ipilimumab

2. Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

3. PD-1 blockade induces responses by inhibiting adaptive immune resistance

4. Melanoma

5. Survival of patients with advanced metastatic melanoma: the impact of novel therapies–update 2017

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