Transmembrane TNF-TNFR2 signaling as a critical immunoregulatory node in pancreatic cancer-Reference-Cited by-同舟云学术

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Transmembrane TNF-TNFR2 signaling as a critical immunoregulatory node in pancreatic cancer

Published:2024-03-12 Issue:1 Volume:13 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Dickey Erin M.¹,Bianchi Anna¹,Amirian Haleh¹,Hosein Peter J.²³,Faustman Denise⁴,Brambilla Roberta⁵,Datta Jashodeep¹³^ORCID

Affiliation:

1. Division of Surgical Oncology, DeWitt Daughtry Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA

2. Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA

3. Sylvester Comprehensive Cancer Center, Miami, FL, USA

4. Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

5. The Miami Project to Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA

Funder

American College of Surgeons

National Institutes of Health

Pancreatic Cancer Action Network

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2024.2326694

Reference10 articles.

1. Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer

2. Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer

3. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

4. Tumor-necrosis factor is a master of T cell exhaustion

5. TNFR2 blockade alone or in combination with PD‐1 blockade shows therapeutic efficacy in murine cancer models

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