Overexpression of CCL-20 and CXCL-8 genes enhances tumor escape and resistance to cemiplimab, a programmed cell death protein-1 (PD-1) inhibitor, in patients with locally advanced and metastatic cutaneous squamous cell carcinoma

Author:

De Falco Vincenzo1ORCID,Napolitano Stefania1ORCID,Franco Renato2,Zito Marino Federica2,Formisano Luigi3,Esposito Daniela3,Suarato Gabriella1,Napolitano Rossella1,Esposito Alfonso1,Caraglia Francesco1,Giugliano Maria Cristina1,Cioli Eleonora1,Famiglietti Vincenzo1,Bianco Roberto3,Argenziano Giuseppe4,Ronchi Andrea2,Ciardiello Davide15,Nardone Valerio6,D’Ippolito Emma6,Del Tufo Sara6,Ciardiello Fortunato1,Troiani Teresa1ORCID

Affiliation:

1. Medical Oncology Unit, Department of Precision Medicine, Università della Campania “Luigi Vanvitelli”, Naples, Italy

2. Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, via Luciano Armanni, Naples, Italy

3. Department of Clinical Medicine and Surgery, University of Naples “Federico II”, Napoli, Italy

4. Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, Italy

5. Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Milan, Italy

6. Radiology Unit, Department of Precision Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, Italy

Publisher

Informa UK Limited

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