A phase 1 trial extension to assess immunologic efficacy and safety of prime-boost vaccination with VXM01, an oral T cell vaccine against VEGFR2, in patients with advanced pancreatic cancer

Author:

Schmitz-Winnenthal Friedrich H.1,Hohmann Nicolas2ORCID,Schmidt Thomas1ORCID,Podola Lilli34,Friedrich Tobias5,Lubenau Heinz6,Springer Marco6,Wieckowski Sébastien7ORCID,Breiner Klaus M.7,Mikus Gerd2ORCID,Büchler Markus W.1,Keller Anne-Valerie6,Koc Ruhan1,Springfeld Christoph4,Knebel Phillip1,Bucur Mariana3,Grenacher Lars8ORCID,Haefeli Walter E.2,Beckhove Philipp34

Affiliation:

1. Department of General, Abdominal and Transplant Surgery, Heidelberg University Hospital, Heidelberg, Germany

2. Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Heidelberg, Germany

3. Regensburg Center for Interventional Immunology (RCI), University Hospital Regensburg, Regensburg, Germany

4. Medical Oncology, National Center for Tumor Diseases, Heidelberg, Germany

5. Diagnostic and Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany

6. VAXIMM GmbH, Mannheim, Germany

7. VAXIMM AG, Basel, Switzerland

8. Diagnostic Munich, Diagnostic Prevention and Imaging Center, Munich, Germany

Funder

VAXIMM AG

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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