Immune checkpoint blockade therapy mitigates systemic inflammation and affects cellular FLIP-expressing monocytic myeloid-derived suppressor cells in non-progressor non-small cell lung cancer patients

Author:

Adamo Annalisa1,Frusteri Cristina1,Pilotto Sara2,Caligola Simone3,Belluomini Lorenzo2,Poffe Ornella1,Giacobazzi Luca1,Dusi Silvia3,Musiu Chiara1,Hu Yushu1,Wang Tian1,Rizzini Davide1,Vella Antonio1,Canè Stefania3,Sartori Giulia2,Insolda Jessica2,Sposito Marco2,Incani Ursula Cesta2,Carbone Carmine4,Piro Geny4,Pettinella Francesca5,Qi Fang6,Wang Dali6,Sartoris Silvia1,De Sanctis Francesco1,Scapini Patrizia5,Dusi Stefano5,Cassatella Marco Antonio5,Bria Emilio3,Milella Michele2,Bronte Vincenzo3,Ugel Stefano1ORCID

Affiliation:

1. Immunology section, Department of Medicine University and Hospital Trust of Verona, Verona, Italy

2. Oncology section, Department of Engineering for Innovative Medicine and Hospital Trust of Verona, Verona, Italy

3. Veneto Institute of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IOV-IRCCS), Padova, Italy

4. Medical Oncology, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy

5. General Pathology section, Department of Medicine University of Verona, Verona, Italy

6. Department of Burns and Plastic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, P.R. China

Funder

Fondazione Italiana per la Ricerca sul Cancro

Cancer Research Institute

Università Cattolica del Sacro Cuore

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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