Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients

Author:

García-Mulero Sandra12,Fornelino Roberto1,Punta Marco3,Lise Stefano3,Varela Mar4,del Carpio Luis P.5,Moreno Rafael5,Costa-García Marcel5,Rieder Dietmar6,Trajanoski Zlatko6,Gros Alena7,Alemany Ramón5,Piulats Josep María8,Sanz-Pamplona Rebeca19

Affiliation:

1. Unit of Biomarkers and Susceptibility, Oncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL) and CIBERESP, Barcelona, Spain

2. Anatomy Unit, Department of Pathology and Experimental Therapy, and Department of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain

3. Bioinformatics Core, Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK

4. Department of Pathology, Bellvitge University Hospital, Barcelona, Spain

5. Procure Program, Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain

6. Institute of Bioinformatics, Biocenter, Medical University of Innsbruck, Innsbruck, Austria

7. Tumor Immunology and Immunotherapy, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain

8. Department of Medical Oncology, ICO, IDIBELL and CIBERONC, Barcelona, Spain

9. Institute for Health Research Aragon (IISA), ARAID Foundation, Aragon Government, University Hospital Lozano Blesa, Zaragoza, Spain

Funder

Instituto de Salud Carlos III

Generalitat de Catalunya

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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