A phase Ⅱ, randomized, controlled trial to evaluate the safety and immunogenicity of a Sabin strain-based inactivated polio vaccine

Author:

Tang Rong1,Li Guifan2,Zhang Chengfu3,Zhi Hengkui4,Zhu Jiahong3,Wang Jianjun4,Liang Qi1,Hu Yuemei1,Li Changgui5

Affiliation:

1. Department of Vaccine Clinical Evaluation, Jiangsu Provincial Center for Disease Control and Prevention (Public Health Research Institute of Jiangsu Province), Jiangsu, China

2. Department of Registration, Beijing Minhai Biotechnology Co. Ltd, Beijing, China

3. Department of Infectious Disease Control and Prevention, Lianshui County Center for Disease Control and Prevention, Lianshui, Jiangsu, China

4. Department of Infectious Disease Control and Prevention, Dafeng County Center for Disease Control and Prevention, Dafeng, Jiangsu, China

5. Division of Respiratory Virus Vaccines, National Institute for Food and Drug Control, Beijing, China

Funder

Beijing Minhai Biotechnology Co. Ltd

Publisher

Informa UK Limited

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference22 articles.

1. Global Polio Eradication Initiative. Polio prevention. [accessed 2019 July 3]. http://polioeradication.org/polio-today/polio-prevention/.

2. Effect of maternal antibody on the infant immune response to inactivated poliovirus vaccines made from Sabin strains

3. World Health Assembly: Global Eradication of Poliomyelitis by the Year 2000. Geneva (Switzerland): World Health Organization; 1988.

4. Immunogenicity of Two Different Sequential Schedules of Inactivated Polio Vaccine Followed by Oral Polio Vaccine Versus Oral Polio Vaccine Alone in Healthy Infants in China

5. Vaccine-Associated Paralytic Poliomyelitis: A Review of the Epidemiology and Estimation of the Global Burden

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