An open-label, non-randomized study investigating the safety and efficacy of smallpox vaccine, LC16, as post-exposure prophylaxis for mpox
Author:
Affiliation:
1. Centre for Clinical Sciences, National Centre for Global Health and Medicine, Tokyo, Japan
2. Disease Control and Prevention Centre, National Centre for Global Health and Medicine, Tokyo, Japan
Funder
Health, Labour and Welfare Administration Promotion Survey Project Grant
Ministry of Health, Labour and Welfare
Publisher
Informa UK Limited
Subject
Pharmacology,Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/21645515.2023.2242219
Reference30 articles.
1. World Health Organization. Mpox (monkeypox) outbreak: global trends; 2022 [accessed 2023 Apr 10].: https://worldhealthorg.shinyapps.io/mpx_global/.
2. Human Monkeypox
3. Comprehensive update on the monkeypox outbreak
4. Emergence of Monkeypox as the Most Important Orthopoxvirus Infection in Humans
5. Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022
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1. Vaccines against mpox: MVA-BN and LC16m8;Expert Review of Vaccines;2024-09
2. Global perspectives on smallpox vaccine against monkeypox: a comprehensive meta-analysis and systematic review of effectiveness, protection, safety and cross-immunogenicity;Emerging Microbes & Infections;2024-08-16
3. Enhanced Immune Responses in Mice by Combining the Mpox Virus B6R-Protein and Aluminum Hydroxide-CpG Vaccine Adjuvants;Vaccines;2024-07-15
4. Safety and Effectiveness of LC16m8 for Pre-Exposure Prophylaxis against mpox in a High-Risk Population: An Open-Label Randomized Trial;2024-06-07
5. Two noncompeting human neutralizing antibodies targeting MPXV B6 show protective effects against orthopoxvirus infections;Nature Communications;2024-05-31
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