In vivo antiviral efficacy of LCTG-002, a pooled, purified human milk secretory IgA product, against SARS-CoV-2 in a murine model of COVID-19-Reference-Cited by-同舟云学术

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In vivo antiviral efficacy of LCTG-002, a pooled, purified human milk secretory IgA product, against SARS-CoV-2 in a murine model of COVID-19

Published:2024-01-22 Issue:1 Volume:20 Page:
ISSN:2164-5515
Container-title:Human Vaccines & Immunotherapeutics
language:en
Short-container-title:Human Vaccines & Immunotherapeutics

Author:

Mane Viraj¹,Mehta Rikin¹,Alvarez Nadine²,Sharma Vijeta²,Park Steven²,Fox Alisa³,DeCarlo Claire³,Yang Xiaoqi³,Perlin David S.²,Powell Rebecca L. R.³

Affiliation:

1. Lactiga US, Inc. 675 US-1, North Brunswick, NJ, USA

2. Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA

3. Icahn School of Medicine at Mount Sinai, Department of Medicine, Division of Infectious Diseases, New York, NY, USA

Funder

Icahn School of Medicine at Mount Sinai

National Institutes of Health

New Jersey Commission on Science, Innovation and Technology

Lactiga

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/21645515.2024.2303226

Reference50 articles.

1. Engineering the Mucus Barrier

2. Immunoglobulin A Mucosal Immunity and Altered Respiratory Epithelium in Cystic Fibrosis

3. Glycans on Secretory Component Participate in Innate Protection against Mucosal Pathogens

4. Multi-Faceted Functions of Secretory IgA at Mucosal Surfaces

5. Immunoglobulin A

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