Immunogenicity and safety of a booster dose of the hepatitis B vaccine HepB-CpG (HEPLISAV-B®) compared with HepB-Eng (Engerix-B®) and HepB-AS04 (Fendrix®) in adults receiving hemodialysis who previously received hepatitis B vaccination and are not seroprotected: Results of a randomized, multicenter phase 3 study

Author:

Girndt Matthias1,Plüer Manfred2,Dellanna Frank3,Michelsen Ann K.4,Beige Joachim5,Toussaint Kai6,Wehweck Hubert J.7,Koch Michael8,Hafezi Rachti Syrus9,Faust Justus10,Bosselmann Hans-Peter11,Witzke Oliver12,Janssen Robert S.13,

Affiliation:

1. Department of Internal Medicine II, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany

2. Nephrology, KfH-Nierenzentrum Berlin-Neukölln, in Berlin-Neukölln, Germany

3. Kidney and Dialysis Center, MVZ DaVita Rhein Ruhr, Düsseldorf, Germany

4. Internal Medicine, MVZ Lütten Klein, Nephrocare Rostock GmbH, Rostock, Germany

5. Department of Nephrology and Kuratorium for Dialysis and Transplantation Renal Unit, Hospital St. Georg, Martin‐Luther‐University Halle/Wittenberg, Leipzig, Germany

6. Lipid Clinic, Nephrocare Hamburg-Barmbek, Hamburg, Germany

7. Internal Medicine, KfH, Nierenzentrum, Munich, Germany

8. Center of Nephrology, Mettmann, Germany

9. Nierenzentrum Mannheim, Mannheim-Käfertal, Germany

10. Internal Medicinem Regulatory and Medical Affairs, Nephrologische Gemeinschaftspraxis, Mainz, Germany

11. Klinik für Nieren- und Hochdruckkrankheiten and Bereich Endokrinologie und Stoffwechselkrankheiten, Otto-von-Guericke-Universität Magdeburg, Magdeburg, Germany

12. Department of Infectious Diseases, West German Centre of Infectious Diseases, Universitätsmedizin Essen, University Duisburg-Essen, Essen, Germany

13. Dynavax Technologies Corporation, Emeryville, California, USA

Funder

Dynavax Technologies Corporation

Publisher

Informa UK Limited

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference25 articles.

1. World Health Organization. Global progress report on HIV, viral hepatitis and sexually transmitted infections. 2021 Jul 15 [accessed 2022 Aug 31]. https://www.who.int/publications/i/item/9789240027077.

2. United States Renal Data System. 2019 USRDS annual data report: epidemiology of kidney disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda (MD); 2018.

3. The European Renal Association – European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report 2015: a summary

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