Long-term immunogenicity and immune memory response to the hepatitis B antigen in the RTS,S/AS01E malaria vaccine in African children: a randomized trial

Author:

Valéa Innocent12,Adjei Samuel3,Usuf Effua4ORCID,Traore Ousmane1,Ansong Daniel3,Tinto Halidou1,Owusu Boateng Harry3,Some Athanase Mwinessobaonfou1,Buabeng Patrick3,Vekemans Johan4,Kotey Amos3,Vandoolaeghe Pascale4,Cullinane Mark4,Traskine Magali4,Ouedraogo Florence1,Sambian David3,Lievens Marc4,Tahita Marc Christian1,Jongert Erik4,Lompo Palpouguini1,Idriss Ali3,Borys Dorota4,Ouedraogo Sayouba1,Prempeh Frank3,Schuerman Lode4,Sorgho Hermann1,Agbenyega Tsiri3

Affiliation:

1. Unité de Recherche Clinique de Nanoro, Institut de Recherche en Sciences de la Santé, Nanoro, Burkina Faso

2. IRSS, Centre Muraz, Bobo-Dioulasso, Burkina Faso

3. School of Medical Sciences, KNUST (Agogo Presbyterian Hospital), Kumasi, Ghana

4. Vaccine, GSK, Wavre, Belgium

Funder

GlaxoSmithKline Biologicals SA

Publisher

Informa UK Limited

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference14 articles.

1. European Medicines Agency. Committee for Medicinal Products for Human Use (CHMP). Assessment Report: MosquirixTM. [Accessed 2018 Nov 5]. http://bit.ly/2paE1uw.

2. World Health Organization. Hepatitis B. Key facts; July 2019 [Accessed 2019 Jul 12]. https://www.who.int/en/news-room/fact-sheets/detail/hepatitis-b.

3. World Health Organization. WHO position paper on hepatitis B vaccines. Weekly epidemiological record No. 40. 2009; 84:405–20. [Accessed Apr 2019]. https://www.who.int/wer/2009/wer8440.pdf?ua=1.

4. Safety and efficacy of the RTS,S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

5. A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

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