Repurposing naproxen as a potential nucleocapsid antagonist of beta-coronaviruses: targeting a conserved protein in the search for a broad-spectrum treatment option-Reference-Cited by-同舟云学术

Repurposing naproxen as a potential nucleocapsid antagonist of beta-coronaviruses: targeting a conserved protein in the search for a broad-spectrum treatment option

Published:2024-02-26 Issue: Volume: Page:1-16
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Valadan Reza¹²,Alizadeh-Navaei Reza³^ORCID,Lagzian Milad⁴^ORCID,Saeedi Majid⁵⁶,Roozbeh Fatemeh⁷,Hedayatizadeh-Omran Akbar³,Amanlou Massoud⁸^ORCID

Affiliation:

1. Department of Immunology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran

2. Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran

3. Gastrointestinal Cancer Research Center, Non-Communicable Disease Institute, Mazandaran University of Medical Sciences, Sari, Iran

4. Department of Biology, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran

5. Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran

6. Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran

7. Infectious Specialist, Mazandaran University of Medical Sciences, Sari, Iran

8. Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Funder

Mazandaran University of Medical Sciences

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2024.2321245

Reference51 articles.

1. Protein structure prediction

2. Efficacy of naproxen in the management of patients hospitalized with COVID-19 infection: A randomized, double-blind, placebo-controlled, clinical trial

3. The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral Structure, Biological Functions, and a Potential Target for Drug or Vaccine Mitigation

4. Naproxen

5. Ribonucleocapsid assembly/packaging signals in the genomes of the coronaviruses SARS-CoV and SARS-CoV-2: detection, comparison and implications for therapeutic targeting