Investigating the role of functional mutations in leucine binding to Sestrin2 in aging and age-associated degenerative pathologies using structural and molecular simulation approaches-Reference-Cited by-同舟云学术

Investigating the role of functional mutations in leucine binding to Sestrin2 in aging and age-associated degenerative pathologies using structural and molecular simulation approaches

Published:2024-04-30 Issue: Volume: Page:1-13
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Khan Abbas¹,Zahid Muhammad Ammar¹,Shahab Muhammad²,Al-Zoubi Raed M.³⁴⁵,Shkoor Mohanad⁶,Benameur Tarek⁷,Agouni Abdelali¹⁸

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, Doha, Qatar

2. Department of Chemistry, Beijing University of Chemical Technology (BUCT), Beijing, China

3. Surgical Research Section, Department of Surgery, Hamad Medical Corporation, Doha, Qatar

4. Department of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha, Qatar

5. Department of Chemistry, Jordan University of Science and Technology, Irbid, Jordan

6. Department of Chemistry, College of Arts and Science, Qatar University, Doha, Qatar

7. College of Medicine, King Faisal University, Al-Ahsa, Kingdom of Saudi Arabia

8. Office of Vice President for Research and Graduate Studies, Qatar University, Doha, Qatar

Funder

Qatar National Research Fund

Publisher

Informa UK Limited

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2024.2335289

Reference42 articles.

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2. Stressin' Sestrins take an aging fight

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4. The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

5. Assessing the performance of the MM/PBSA and MM/GBSA methods. 6. Capability to predict protein–protein binding free energies and re-rank binding poses generated by protein–protein docking