Insights into structural dynamics of allosteric binding sites in HCV RNA-dependent RNA polymerase-Reference-Cited by-同舟云学术

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Insights into structural dynamics of allosteric binding sites in HCV RNA-dependent RNA polymerase

Published:2019-05-05 Issue: Volume: Page:1-14
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Mittal Lovika¹,Kumari Anita¹,Suri Charu¹,Bhattacharya Sankar²,Asthana Shailendra¹

Affiliation:

1. Drug Discovery Research Center (DDRC), Translational Health Science and Technology Institute (THSTI), Faridabad, India;

2. Vaccine and Infectious Disease Research Center (VIDRC), Translational Health Science and Technology Institute (THSTI), Faridabad, India

Funder

Science and Engineering Research Board

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2019.1614480

Reference35 articles.

1. Baseline dasabuvir resistance in Hepatitis C virus from the genotypes 1, 2 and 3 and modeling of the NS5B-dasabuvir complex by thein silicoapproach

2. Molecular Mechanism of Viral Resistance to a Potent Non-nucleoside Inhibitor Unveiled by Molecular Simulations

3. Different Molecular Mechanisms of Inhibition of Bovine Viral Diarrhea Virus and Hepatitis C Virus RNA-Dependent RNA Polymerases by a Novel Benzimidazole

4. MEME SUITE: tools for motif discovery and searching

5. Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside Inhibitors

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