How oncogenic mutations activate human MAP kinase 1 (MEK1): a molecular dynamics simulation study

Author:

Liu Ye1,Zhu Jingxuan1,Guo Xiaoqing1,Huang Tianci1,Han Jiarui1,Gao Jianjiong2,Xu Dong34,Han Weiwei1

Affiliation:

1. Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Science, Jilin University, Changchun, China;

2. Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA;

3. Department of Electric Engineering and Computer Science, C.S. Bond Life Sciences Center, University of Missouri, Columbia, MO, USA;

4. College of Computer Science and Technology, Jilin University, Changchun, China

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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