Computational approach identifies protein off-targets for Isoniazid-NAD adduct: hypothesizing a possible drug resistance mechanism inMycobacterium tuberculosis-Reference-Cited by-同舟云学术

Computational approach identifies protein off-targets for Isoniazid-NAD adduct: hypothesizing a possible drug resistance mechanism inMycobacterium tuberculosis

Published:2019-05-16 Issue: Volume: Page:1-14
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Hassan Sameer¹²,Sudhakar Vaishnavi²,Nancy Mary M. Benita²,Babu Rajeshwari²,Doble Mukesh³,Dadar Maryam⁴,Hanna Luke Elizabeth²

Affiliation:

1. Department of Biological and Environmental Sciences, University of Gothenburg, Gothenburg, Sweden;

2. Department of HIV, National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, India;

3. Department of Biotechnology, Indian Institute of Technology, Chennai, Tamil Nadu, India;

4. Education and Extension Organization, Razi Vaccine and Serum Research Institute, Agricultural Research, Karaj, Iran

Funder

Indian Council of Medical Research

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2019.1615987

Reference70 articles.

1. Cysteine Synthase (CysM) of Mycobacterium tuberculosis Is an O-Phosphoserine Sulfhydrylase

2. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

3. UniProt: the Universal Protein knowledgebase

4. Proteome-wide Profiling of Isoniazid Targets in Mycobacterium tuberculosis

5. inhA , a Gene Encoding a Target for Isoniazid and Ethionamide in Mycobacterium tuberculosis

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