Human dopamine transporter: the first implementation of a combined in silico/in vitro approach revealing the substrate and inhibitor specificities

Author:

Djikic Teodora1,Martí Yasmina23,Spyrakis Francesca4,Lau Thorsten2,Benedetti Paolo5,Davey Gavin6,Schloss Patrick3,Yelekci Kemal1ORCID

Affiliation:

1. Department of Bioinformatics and Genetics, Kadir Has University, Cibali campus, Fatih 34083, Istanbul, Turkey

2. Hector Institute for Translational Brain Research, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim J5, 68159, Germany

3. Biochemical Laboratory, Psychiatry and Psychotherapy Department, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim J5, 68159, Germany

4. Department of Drug Science and Technology, University of Turin, via P. Giuria 9, Turin 10125, Italy

5. Department of Chemistry, Biology and Biotechnology, University of Perugia, via Elce di sotto 8, Perugia 06123, Italy

6. School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland

Funder

Marie Curie Fellowship, Training in Neurodegeneration, Therapeutics, Intervention and Neurorepair

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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