In silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N-terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with low density lipoprotein receptor related protein 5/6-Reference-Cited by-同舟云学术

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In silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N-terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with low density lipoprotein receptor related protein 5/6

Published:2018-11-17 Issue:10 Volume:37 Page:2564-2580
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Sadeghi Solmaz¹²,Poorebrahim Mansour¹²,Rahimi Hamzeh²,Karimipoor Morteza²,Azadmanesh Kayhan³,Khorramizadeh Mohammad Reza⁴,Teimoori-Toolabi Ladan¹²

Affiliation:

1. Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran;

2. Molecular Medicine Department, Pasteur Institute of Iran, Tehran, Iran;

3. Virology Department, Pasteur Institute of Iran, Tehran, Iran;

4. Biosensor Research Center, Endocrinology and Metabolism Molecular-Cellular Research Institute, Tehran University of Medical Sciences, Tehran, Iran

Funder

Tehran University of Medical Sciences

Pasteur Institute of Iran

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2018.1491891

Reference79 articles.

1. Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

2. Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6

3. A colipase fold in the carboxy-terminal domain of the Wnt antagonists – the Dickkopfs

4. Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells

5. Protein structure validation by generalized linear model root-mean-square deviation prediction

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2. Integration of Long Non-Coding RNA and mRNA Profiling Reveals the Mechanisms of Different Dietary NFC/NDF Ratios Induced Rumen Development in Calves;Animals;2022-03-03

3. In-silico identification of new inhibitors for Low-density lipoprotein receptor-related protein6 (LRP6);Journal of Biomolecular Structure and Dynamics;2020-12-18

4. Novel Small Molecules against Two Binding Sites of Wnt2 Protein as potential Drug Candidates for Colorectal Cancer: A Structure Based Virtual Screening Approach;IRAN J PHARM RES;2020

5. Dihydrotestosterone inhibits arylsulfatase B and Dickkopf Wnt signaling pathway inhibitor (DKK)‐3 leading to enhanced Wnt signaling in prostate epithelium in response to stromal Wnt3A;The Prostate;2019-02-22

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