How does the novel T315L mutation of breakpoint cluster region-abelson (BCR-ABL) kinase confer resistance to ponatinib: a comparative molecular dynamics simulation study-Reference-Cited by-同舟云学术

How does the novel T315L mutation of breakpoint cluster region-abelson (BCR-ABL) kinase confer resistance to ponatinib: a comparative molecular dynamics simulation study

Published:2019-02-05 Issue:1 Volume:38 Page:89-100
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Zhang Hao¹,He Xinheng¹,Ni Duan¹,Mou Linkai²,Chen Xiangyu³,Lu Shaoyong¹

Affiliation:

1. Department of Pathophysiology Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University, School of Medicine, Shanghai, China;

2. Department of Urology, Affiliated Hospital of Weifang Medicinal University, Wei fang, Shandong, China;

3. Department of Medicinal Laboratory, Weifang Medicinal University, Weifang, Shandong, China

Funder

National Natural Science Foundation of China

Shanghai Health and Family Planning Commission

The Fundamental Research Funds for the Central Universities

Shandong Provincial Natural Science Foundation

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2019.1567390

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4. Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia

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