FMS-like tyrosine kinase-3 (FLT3) inhibitors with better binding affinity and ADMET properties than sorafenib and gilteritinib against acute myeloid leukemia: in silico studies-Reference-Cited by-同舟云学术

FMS-like tyrosine kinase-3 (FLT3) inhibitors with better binding affinity and ADMET properties than sorafenib and gilteritinib against acute myeloid leukemia: in silico studies

Published:2021-09-06 Issue: Volume: Page:1-12
ISSN:0739-1102
Container-title:Journal of Biomolecular Structure and Dynamics
language:en
Short-container-title:Journal of Biomolecular Structure and Dynamics

Author:

Egbuna Chukwuebuka¹²³^ORCID,Patrick-Iwuanyanwu Kingsley C.¹²,Onyeike Eugene N.¹²,Khan Johra⁴⁵^ORCID,Alshehri Bader⁴⁵

Affiliation:

1. Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR), University of Port-Harcourt, Port Harcourt, Rivers State, Nigeria

2. Department of Biochemistry, Faculty of Science, University of Port Harcourt, Port Harcourt, Rivers State, Nigeria

3. Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria

4. Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah, Saudia Arabia

5. Health and Basic Sciences Research Center, Majmaah University, Majmaah, Saudi Arabia

Funder

Deanship of Scientific Research at Majmaah University

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

Link

https://www.tandfonline.com/doi/pdf/10.1080/07391102.2021.1969286

Reference66 articles.

1. American Physiological Society. (2019). FMS-like tyrosine kinase 3/FLT3: From basic science to clinical implications. https://journals.physiology.org/doi/full/10.1152/physrev.00029.2018. https://doi.org/10.1152/physrev.00029.2018

2. Bioavailability of phytochemicals and its enhancement by drug delivery systems

3. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

4. Dysregulation of haematopoietic stem cell regulatory programs in acute myeloid leukaemia

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