Emetine, a potent alkaloid for the treatment of SARS-CoV-2 targeting papain-like protease and non-structural proteins: pharmacokinetics, molecular docking and dynamic studies

Author:

Snoussi Mejdi12ORCID,Redissi Alaeddine3ORCID,Mosbah Amor3ORCID,De Feo Vincenzo4ORCID,Adnan Mohd1ORCID,Aouadi Kaïss56ORCID,Alreshidi Mousa1ORCID,Patel Mitesh7ORCID,Kadri Adel89,Noumi Emira110

Affiliation:

1. Department of Biology, College of Science, University of Hail, Ha’il, Saudi Arabia

2. Laboratory of Genetics, Biodiversity and Valorization of Bio-resources, Higher Institute of Biotechnology of Monastir, University of Monastir, Monastir, Tunisia

3. ISBST, BVBGR-LR11ES31, Biotechpole Sidi Thabet, University of Manouba, Ariana, Tunisia

4. Department of Pharmacy, University of Salerno, Salerno, Italy

5. Department of Chemistry, College of Science, Qassim University, Buraidah, Saudi Arabia

6. Faculty of Science of Monastir, Laboratory of Hetrocyclic Chemistry, Natural Products and Reactivity, University of Monastir, Monastir, Tunisia

7. Bapalal Vaidya Botanical Research Centre, Department of Biosciences, Veer Narmad South Gujarat University, Surat, India

8. Faculty of Science of Sfax, Department of Chemistry, University of Sfax, Sfax, Tunisia

9. Faculty of Science and Arts in Baljurashi, Albaha University, Al Bahah, Saudi Arabia

10. Laboratory of Bioresources: Integrative Biology and Valorization, (LR14-ES06), University of Monastir, Higher Institute of Biotechnology of Monastir, Monastir, Tunisia

Funder

Scientific Research Deanship at University of Ha’il-Saudi Arabia

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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