Xanthone glucoside 2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one binds to the ATP-binding pocket of glycogen synthase kinase 3β and inhibits its activity: implications in prostate cancer and associated cardiovascular disease risk

Author:

Mangangcha Irengbam Rocky1234,Brojen Singh Raj Kumar5,Lebeche Djamel678,Ali Shakir123ORCID

Affiliation:

1. Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard (Deemed University), Delhi, India

2. School of Interdisciplinary Sciences and Technology, Jamia Hamdard (Deemed University), Delhi, India

3. Bioinformatics Center, BIF, Jamia Hamdard (Deemed University), Delhi, India

4. Department of Zoology, Deshbandhu College, University of Delhi, Delhi, India

5. School of Computational & Integrative Sciences, Jawaharlal Nehru University, Delhi, India

6. Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

7. Diabetes, Obesity and Metabolism Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA

8. Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Publisher

Informa UK Limited

Subject

Molecular Biology,General Medicine,Structural Biology

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